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CVE-2025-11000

Open Babel PQSformat.cpp ReadMolecule null pointer dereference

4.8 MediumFix available

A vulnerability was determined in Open Babel up to 3.1.1. This affects the function PQSFormat::ReadMolecule of the file /src/formats/PQSformat.cpp. This manipulation causes null pointer dereference. The attack is restricted to local execution. The exploit has been publicly disclosed and may be utilized.

Attack profile

How easy it is to exploit

Attack vector
Local
Complexity
Low
Privileges needed
Low
User interaction
None

What an attacker can affect

Confidentiality
None
Integrity
None
Availability
Low

Exploit likelihood

0.25%Up 0.2 points since Sep 26, 2025
90%50%10%1%

What each source reports

CVE List Score used 4.8

Open Babel PQSformat.cpp ReadMolecule null pointer dereference

A vulnerability was determined in Open Babel up to 3.1.1. This affects the function PQSFormat::ReadMolecule of the file /src/formats/PQSformat.cpp. This manipulation causes null pointer dereference. The attack is restricted to local execution. The exploit has been publicly disclosed and may be utilized.

Record
CVE-2025-11000
CVSS 4.0
4.8 MediumCVSS:4.0/AV:L/AC:L/AT:N/PR:L/UI:N/VC:N/VI:N/VA:L/SC:N/SI:N/SA:N/E:P
CVSS 3.1
3.3 LowCVSS:3.1/AV:L/AC:L/PR:L/UI:N/S:U/C:N/I:N/A:L/E:P/RL:X/RC:R
CVSS 3.0
3.3 LowCVSS:3.0/AV:L/AC:L/PR:L/UI:N/S:U/C:N/I:N/A:L/E:P/RL:X/RC:R
CVSS 2.0
1.7 AV:L/AC:L/Au:S/C:N/I:N/A:P/E:POC/RL:ND/RC:UR
Weakness
CWE-476, CWE-404
Updated
2026-11-02
EUVDEUVD-2025-31206 4.8

Open Babel has out-of-bounds read in PQS lowerit (pre-buffer read)

Record
EUVD-2025-31206
CVSS 4.0
4.8 MediumCVSS:4.0/AV:L/AC:L/AT:N/PR:L/UI:N/VC:N/VI:N/VA:L/SC:N/SI:N/SA:N/E:P
Updated
2026-11-02
GitHub AdvisoriesGHSA-7x26-54jj-cvhr 1.9

Duplicate Advisory: Open Babel has out-of-bounds read in PQS lowerit (pre-buffer read)

Duplicate Advisory

This advisory has been withdrawn because it is a duplicate of GHSA-m982-7q3h-r784. This link is maintained to preserve external references.

Original Description

A vulnerability was determined in Open Babel up to 3.1.1. This affects the function PQSFormat::ReadMolecule of the file /src/formats/PQSformat.cpp. This manipulation causes null pointer dereference. The attack is restricted to local execution. The exploit has been publicly disclosed and may be utilized.

Record
GHSA-7x26-54jj-cvhr
CVSS 4.0
1.9 LowCVSS:4.0/AV:L/AC:L/AT:N/PR:L/UI:N/VC:N/VI:N/VA:L/SC:N/SI:N/SA:N/E:P/CR:X/IR:X/AR:X/MAV:X/MAC:X/MAT:X/MPR:X/MUI:X/MVC:X/MVI:X/MVA:X/MSC:X/MSI:X/MSA:X/S:X/AU:X/R:X/V:X/RE:X/U:X
CVSS 3.1
3.3 LowCVSS:3.1/AV:L/AC:L/PR:L/UI:N/S:U/C:N/I:N/A:L
Weakness
CWE-404
Updated
2026-11-02
GitHub AdvisoriesGHSA-m982-7q3h-r784 4.4

Open Babel has out-of-bounds read in PQS lowerit (pre-buffer read)

Summary

A memory-safety vulnerability in Open Babel's PQS parser caused an out-of-bounds (pre-buffer) read when reading a crafted input file.

Details

The flaw was in the lowerit helper used by the PQS parser. A malformed input caused the helper to read one or more bytes before the start of its input buffer.

Impact

Open Babel is a C++ library and CLI used to read and write chemistry file formats; it is shipped by Linux distributions and embedded in services that may parse untrusted input. Triggering this vulnerability requires the victim to open a malicious PQS file with the obabel tool, the OBConversion API, or any of the language bindings (Python, Ruby, Java, R, Perl, C#, PHP).

Affected versions

All releases up to and including 3.1.1.

Patched version

3.2.0 (released 2026-05-26).

Patch

Fix commit: https://github.com/openbabel/openbabel/commit/f4a5ebae Fixes consolidated in #2913.

A minimized reproducer for this CVE is checked in under test/files/fuzz_regress/ and is exercised on every CI build under ASAN+UBSAN by the fuzzregresstest harness.

Credit

Reported via OSS-Fuzz.

Record
GHSA-m982-7q3h-r784
CVSS 3.1
4.4 MediumCVSS:3.1/AV:L/AC:L/PR:N/UI:R/S:U/C:L/I:N/A:L
Weakness
CWE-125, CWE-404
Updated
2026-11-02
NVD 1.9

A vulnerability was determined in Open Babel up to 3.1.1. This affects the function PQSFormat::ReadMolecule of the file /src/formats/PQSformat.cpp. This manipulation causes null pointer dereference. The attack is restricted to local execution. The exploit has been publicly disclosed and may be utilized.

Record
CVE-2025-11000
CVSS 4.0
1.9 LowCVSS:4.0/AV:L/AC:L/AT:N/PR:L/UI:N/VC:N/VI:N/VA:L/SC:N/SI:N/SA:N/E:P/CR:X/IR:X/AR:X/MAV:X/MAC:X/MAT:X/MPR:X/MUI:X/MVC:X/MVI:X/MVA:X/MSC:X/MSI:X/MSA:X/S:X/AU:X/R:X/V:X/RE:X/U:X
CVSS 3.1
3.3 LowCVSS:3.1/AV:L/AC:L/PR:L/UI:N/S:U/C:N/I:N/A:L
CVSS 3.1
5.5 MediumCVSS:3.1/AV:L/AC:L/PR:L/UI:N/S:U/C:N/I:N/A:H
CVSS 2.0
1.7 LowAV:L/AC:L/Au:S/C:N/I:N/A:P
Weakness
CWE-404, CWE-476
Updated
2026-11-02
OSV 1.9

Open Babel PQSformat.cpp ReadMolecule null pointer dereference

A vulnerability was determined in Open Babel up to 3.1.1. This affects the function PQSFormat::ReadMolecule of the file /src/formats/PQSformat.cpp. This manipulation causes null pointer dereference. The attack is restricted to local execution. The exploit has been publicly disclosed and may be utilized.

Record
CVE-2025-11000
CVSS 4.0
1.9 LowCVSS:4.0/AV:L/AC:L/AT:N/PR:L/UI:N/VC:N/VI:N/VA:L/SC:N/SI:N/SA:N/E:P
Weakness
CWE-404, CWE-476
Updated
2026-11-02
Show 6 moreShow less
OSVDEBIAN-CVE-2025-11000 5.5

A vulnerability was determined in Open Babel up to 3.1.1. This affects the function PQSFormat::ReadMolecule of the file /src/formats/PQSformat.cpp. This manipulation causes null pointer dereference. The attack is restricted to local execution. The exploit has been publicly disclosed and may be utilized.

Record
DEBIAN-CVE-2025-11000
CVSS 3.1
5.5 MediumCVSS:3.1/AV:L/AC:L/PR:L/UI:N/S:U/C:N/I:N/A:H
Updated
2026-11-02
OSVGHSA-7x26-54jj-cvhr 1.9

Duplicate Advisory: Open Babel has out-of-bounds read in PQS lowerit (pre-buffer read)

Duplicate Advisory

This advisory has been withdrawn because it is a duplicate of GHSA-m982-7q3h-r784. This link is maintained to preserve external references.

Original Description

A vulnerability was determined in Open Babel up to 3.1.1. This affects the function PQSFormat::ReadMolecule of the file /src/formats/PQSformat.cpp. This manipulation causes null pointer dereference. The attack is restricted to local execution. The exploit has been publicly disclosed and may be utilized.

Record
GHSA-7x26-54jj-cvhr
CVSS 4.0
1.9 LowCVSS:4.0/AV:L/AC:L/AT:N/PR:L/UI:N/VC:N/VI:N/VA:L/SC:N/SI:N/SA:N/E:P/CR:X/IR:X/AR:X/MAV:X/MAC:X/MAT:X/MPR:X/MUI:X/MVC:X/MVI:X/MVA:X/MSC:X/MSI:X/MSA:X/S:X/AU:X/R:X/V:X/RE:X/U:X
CVSS 3.1
3.3 LowCVSS:3.1/AV:L/AC:L/PR:L/UI:N/S:U/C:N/I:N/A:L
Weakness
CWE-404
Updated
2026-11-02
OSVGHSA-m982-7q3h-r784 4.4

Open Babel has out-of-bounds read in PQS lowerit (pre-buffer read)

Summary

A memory-safety vulnerability in Open Babel's PQS parser caused an out-of-bounds (pre-buffer) read when reading a crafted input file.

Details

The flaw was in the lowerit helper used by the PQS parser. A malformed input caused the helper to read one or more bytes before the start of its input buffer.

Impact

Open Babel is a C++ library and CLI used to read and write chemistry file formats; it is shipped by Linux distributions and embedded in services that may parse untrusted input. Triggering this vulnerability requires the victim to open a malicious PQS file with the obabel tool, the OBConversion API, or any of the language bindings (Python, Ruby, Java, R, Perl, C#, PHP).

Affected versions

All releases up to and including 3.1.1.

Patched version

3.2.0 (released 2026-05-26).

Patch

Fix commit: https://github.com/openbabel/openbabel/commit/f4a5ebae Fixes consolidated in #2913.

A minimized reproducer for this CVE is checked in under test/files/fuzz_regress/ and is exercised on every CI build under ASAN+UBSAN by the fuzzregresstest harness.

Credit

Reported via OSS-Fuzz.

Record
GHSA-m982-7q3h-r784
CVSS 3.1
4.4 MediumCVSS:3.1/AV:L/AC:L/PR:N/UI:R/S:U/C:L/I:N/A:L
Weakness
CWE-125, CWE-404
Updated
2026-11-02
OSVPYSEC-2026-2785 4.4

Open Babel has out-of-bounds read in PQS lowerit (pre-buffer read)

Summary

A memory-safety vulnerability in Open Babel's PQS parser caused an out-of-bounds (pre-buffer) read when reading a crafted input file.

Details

The flaw was in the lowerit helper used by the PQS parser. A malformed input caused the helper to read one or more bytes before the start of its input buffer.

Impact

Open Babel is a C++ library and CLI used to read and write chemistry file formats; it is shipped by Linux distributions and embedded in services that may parse untrusted input. Triggering this vulnerability requires the victim to open a malicious PQS file with the obabel tool, the OBConversion API, or any of the language bindings (Python, Ruby, Java, R, Perl, C#, PHP).

Affected versions

All releases up to and including 3.1.1.

Patched version

3.2.0 (released 2026-05-26).

Patch

Fix commit: https://github.com/openbabel/openbabel/commit/f4a5ebae Fixes consolidated in #2913.

A minimized reproducer for this CVE is checked in under test/files/fuzz_regress/ and is exercised on every CI build under ASAN+UBSAN by the fuzzregresstest harness.

Credit

Reported via OSS-Fuzz.

Record
PYSEC-2026-2785
CVSS 3.1
4.4 MediumCVSS:3.1/AV:L/AC:L/PR:N/UI:R/S:U/C:L/I:N/A:L
Updated
2026-11-02
OSVUBUNTU-CVE-2025-11000 1.9

A vulnerability was determined in Open Babel up to 3.1.1. This affects the function PQSFormat::ReadMolecule of the file /src/formats/PQSformat.cpp. This manipulation causes null pointer dereference. The attack is restricted to local execution. The exploit has been publicly disclosed and may be utilized.

Record
UBUNTU-CVE-2025-11000
CVSS 4.0
1.9 LowCVSS:4.0/AV:L/AC:L/AT:N/PR:L/UI:N/VC:N/VI:N/VA:L/SC:N/SI:N/SA:N/E:P
CVSS 3.1
5.5 MediumCVSS:3.1/AV:L/AC:L/PR:L/UI:N/S:U/C:N/I:N/A:H
CVSS 3.1
3.3 LowCVSS:3.1/AV:L/AC:L/PR:L/UI:N/S:U/C:N/I:N/A:L
Updated
2026-11-02
OSVopenSUSE-SU-2026:21190-1 No score

Security update for openbabel

This update for openbabel fixes the following issues:

Changes in openbabel:

  • Update to version 3.2.0:
    • Add an L-BFGS optimizer, used by default for gen3d and conformer searches
    • New macrocycle ring builder (Dale codes) for better initial 3D geometry of large rings
    • Add KET (Ketcher JSON) and ChemicalJSON (.cjson) format support
    • Drop Python 2 support; Python 3.13 supported
    • Faster, vectorized distance-geometry implementation
    • Full CMake 4 compatibility and modernized build
    • Backwards compatible with 3.0 and 3.1
    • Fix many crash and memory-safety bugs found via OSS-Fuzz and TALOS, including the following security issues: CVE-2022-37331 (boo#1217676), CVE-2022-41793, CVE-2022-42885, CVE-2022-43467, CVE-2022-43607, CVE-2022-44451, CVE-2022-46280, CVE-2022-46289, CVE-2022-46290, CVE-2022-46291, CVE-2022-46292, CVE-2022-46294, CVE-2022-46295, CVE-2025-10994, CVE-2025-10995, CVE-2025-10996, CVE-2025-10997, CVE-2025-10998, CVE-2025-10999, CVE-2025-11000, CVE-2026-2704 (boo#1258501), CVE-2026-2705 (boo#1258507) and CVE-2026-3408 (boo#1259041)
Record
openSUSE-SU-2026:21190-1
Updated
2026-11-02

Affected products

Affected packages

Affected packages
PackageAffectedFixed
openbabel
PyPI
before 3.2.0
3.2.0
openbabel
Debian:12
All versions, plus listed versions
3.1.1+dfsg-103.1.1+dfsg-113.1.1+dfsg-123.1.1+dfsg-133.1.1+dfsg-14
Show 4 moreShow less
3.1.1+dfsg-15~exp3.1.1+dfsg-93.2.0+dfsg-13.2.0+dfsg-1~exp
None known
openbabel
Debian:13
All versions, plus listed versions
3.1.1+dfsg-123.1.1+dfsg-133.1.1+dfsg-143.1.1+dfsg-15~exp3.2.0+dfsg-13.2.0+dfsg-1~exp
None known
openbabel
Debian:14
All versions, plus listed versions
3.1.1+dfsg-123.1.1+dfsg-133.1.1+dfsg-143.1.1+dfsg-15~exp3.2.0+dfsg-13.2.0+dfsg-1~exp
None known
openbabel
PyPI
before 3.2.0, plus listed versions
1.81.8.11.8.21.8.31.8.4
Show 6 moreShow less
2.4.02.4.13.0.03.0.0a13.1.13.1.1.1
3.2.0
openbabel
Ubuntu:16.04:LTS
All versions, plus listed versions
2.3.2+dfsg-2.22.3.2+dfsg-2.2build1
None known
openbabel
Ubuntu:18.04:LTS
All versions, plus listed versions
2.3.2+dfsg-3build1
None known
openbabel
Ubuntu:20.04:LTS
All versions, plus listed versions
2.4.1+dfsg-32.4.1+dfsg-3build12.4.1+dfsg-5.12.4.1+dfsg-63.0.0+dfsg-33.0.0+dfsg-3ubuntu3
None known
openbabel
Ubuntu:22.04:LTS
All versions, plus listed versions
3.1.1+dfsg-6ubuntu13.1.1+dfsg-6ubuntu5
None known
openbabel
Ubuntu:24.04:LTS
All versions, plus listed versions
3.1.1+dfsg-9build23.1.1+dfsg-9ubuntu13.1.1+dfsg-9ubuntu23.1.1+dfsg-9ubuntu43.1.1+dfsg-9ubuntu5
None known
Show 4 moreShow less
Affected packages
PackageAffectedFixed
openbabel
Ubuntu:25.10
All versions, plus listed versions
3.1.1+dfsg-11ubuntu33.1.1+dfsg-11ubuntu4
None known
openbabel
Ubuntu:26.10
All versions, plus listed versions
3.1.1+dfsg-11ubuntu53.1.1+dfsg-14ubuntu2
None known
openbabel
Ubuntu:26.04:LTS
All versions, plus listed versions
3.1.1+dfsg-11ubuntu43.1.1+dfsg-11ubuntu5
None known
openbabel
openSUSE:Leap 16.0
From an advisory covering 23 CVEs
before 3.2.0-bp160.1.1
3.2.0-bp160.1.1

History

History
RecordedChangedSources
affected, facts
affected
first indexedCVE List, EUVD, GitHub Advisories, NVD, OSV

Dates are when Every CVE recorded each change. Upstream dates may differ.

In short

CVE-2025-11000 is a medium vulnerability (CVSS 4.8) in Openbabel Open Babel, published September 26, 2025. No source lists public exploit code. EPSS puts the chance of exploitation in the next 30 days at 0.25%, the 15th percentile. Fixed in openbabel 3.2.0.

References

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