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CVE-2025-54808

Oxford Nanopore Technologies MinKNOW Insufficiently Protected Credentials

7.3 High

Oxford Nanopore Technologies' MinKNOW software at or prior to version 24.11 stores authentication tokens in a file located in the system's temporary directory (/tmp) on the host machine. This directory is typically world-readable, allowing any local user or application to access the token. If the token is leaked (e.g., via malware infection or other local exploit), and remote access is enabled, it can be used to establish unauthorized remote connections to the sequencer. Remote access must be enabled for remote exploitation to succeed. This may occur either because the user has enabled remote access for legitimate operational reasons or because malware with elevated privileges (e.g., sudo access) enables it without user consent. This vulnerability can be chained with remote access capabilities to generate a developer token from a remote device. Developer tokens can be created with arbitrary expiration dates, enabling persistent access to the sequencer and bypassing standard authentication mechanisms.

Attack profile

How easy it is to exploit

Attack vector
Local
Complexity
Low
Privileges needed
Low
User interaction
None

What an attacker can affect

Confidentiality
High
Integrity
High
Availability
High

Exploit likelihood

0.16%Up 0.1 points since Oct 24, 2025
90%50%10%1%

What each source reports

CVE List Score used 7.3

Oxford Nanopore Technologies MinKNOW Insufficiently Protected Credentials

Oxford Nanopore Technologies' MinKNOW software at or prior to version 24.11 stores authentication tokens in a file located in the system's temporary directory (/tmp) on the host machine. This directory is typically world-readable, allowing any local user or application to access the token. If the token is leaked (e.g., via malware infection or other local exploit), and remote access is enabled, it can be used to establish unauthorized remote connections to the sequencer. Remote access must be enabled for remote exploitation to succeed. This may occur either because the user has enabled remote access for legitimate operational reasons or because malware with elevated privileges (e.g., sudo access) enables it without user consent. This vulnerability can be chained with remote access capabilities to generate a developer token from a remote device. Developer tokens can be created with arbitrary expiration dates, enabling persistent access to the sequencer and bypassing standard authentication mechanisms.

Record
CVE-2025-54808
CVSS 4.0
7.3 HighCVSS:4.0/AV:L/AC:L/AT:P/PR:L/UI:N/VC:H/VI:H/VA:H/SC:N/SI:N/SA:N
CVSS 3.1
7.8 HighCVSS:3.1/AV:L/AC:L/PR:L/UI:N/S:U/C:H/I:H/A:H
Weakness
CWE-522
Updated
2026-11-02
EUVDEUVD-2025-35731 7.3

Oxford Nanopore Technologies' MinKNOW software at or prior to version 24.11 stores authentication tokens in a file located in the system's temporary directory (/tmp) on the host machine. This directory is typically world-readable, allowing any local user or application to access the token. If the token is leaked (e.g., via malware infection or other local exploit), and remote access is enabled, it can be used to establish unauthorized remote connections to the sequencer. Remote access must be enabled for remote exploitation to succeed. This may occur either because the user has enabled remote access for legitimate operational reasons or because malware with elevated privileges (e.g., sudo access) enables it without user consent. This vulnerability can be chained with remote access capabilities to generate a developer token from a remote device. Developer tokens can be created with arbitrary expiration dates, enabling persistent access to the sequencer and bypassing standard authentication mechanisms.

Record
EUVD-2025-35731
CVSS 4.0
7.3 HighCVSS:4.0/AV:L/AC:L/AT:P/PR:L/UI:N/VC:H/VI:H/VA:H/SC:N/SI:N/SA:N
Updated
2026-11-02
GitHub AdvisoriesGHSA-7p36-wh9x-8c9p 7.3

Oxford Nanopore Technologies' MinKNOW software at or prior to version 24.11 stores authentication...

Oxford Nanopore Technologies' MinKNOW software at or prior to version 24.11 stores authentication tokens in a file located in the system's temporary directory (/tmp) on the host machine. This directory is typically world-readable, allowing any local user or application to access the token. If the token is leaked (e.g., via malware infection or other local exploit), and remote access is enabled, it can be used to establish unauthorized remote connections to the sequencer. Remote access must be enabled for remote exploitation to succeed. This may occur either because the user has enabled remote access for legitimate operational reasons or because malware with elevated privileges (e.g., sudo access) enables it without user consent. This vulnerability can be chained with remote access capabilities to generate a developer token from a remote device. Developer tokens can be created with arbitrary expiration dates, enabling persistent access to the sequencer and bypassing standard authentication mechanisms.

Record
GHSA-7p36-wh9x-8c9p
CVSS 4.0
7.3 HighCVSS:4.0/AV:L/AC:L/AT:P/PR:L/UI:N/VC:H/VI:H/VA:H/SC:N/SI:N/SA:N/E:X/CR:X/IR:X/AR:X/MAV:X/MAC:X/MAT:X/MPR:X/MUI:X/MVC:X/MVI:X/MVA:X/MSC:X/MSI:X/MSA:X/S:X/AU:X/R:X/V:X/RE:X/U:X
CVSS 3.1
7.8 HighCVSS:3.1/AV:L/AC:L/PR:L/UI:N/S:U/C:H/I:H/A:H
Weakness
CWE-522
Updated
2026-11-02
NVD 7.3

Oxford Nanopore Technologies' MinKNOW software at or prior to version 24.11 stores authentication tokens in a file located in the system's temporary directory (/tmp) on the host machine. This directory is typically world-readable, allowing any local user or application to access the token. If the token is leaked (e.g., via malware infection or other local exploit), and remote access is enabled, it can be used to establish unauthorized remote connections to the sequencer. Remote access must be enabled for remote exploitation to succeed. This may occur either because the user has enabled remote access for legitimate operational reasons or because malware with elevated privileges (e.g., sudo access) enables it without user consent. This vulnerability can be chained with remote access capabilities to generate a developer token from a remote device. Developer tokens can be created with arbitrary expiration dates, enabling persistent access to the sequencer and bypassing standard authentication mechanisms.

Record
CVE-2025-54808
CVSS 4.0
7.3 HighCVSS:4.0/AV:L/AC:L/AT:P/PR:L/UI:N/VC:H/VI:H/VA:H/SC:N/SI:N/SA:N/E:X/CR:X/IR:X/AR:X/MAV:X/MAC:X/MAT:X/MPR:X/MUI:X/MVC:X/MVI:X/MVA:X/MSC:X/MSI:X/MSA:X/S:X/AU:X/R:X/V:X/RE:X/U:X
CVSS 3.1
7.8 HighCVSS:3.1/AV:L/AC:L/PR:L/UI:N/S:U/C:H/I:H/A:H
Weakness
CWE-522
Updated
2026-11-02

Affected products

History

History
RecordedChangedSources
first indexedCVE List, EUVD, GitHub Advisories, NVD

Dates are when Every CVE recorded each change. Upstream dates may differ.

In short

CVE-2025-54808 is a high vulnerability (CVSS 7.3) in Oxford Nano Technologies Minknow, published October 23, 2025. No source lists public exploit code. EPSS puts the chance of exploitation in the next 30 days at 0.16%, the 5th percentile. No source names a fixed version.

References

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