CVE-2026-31967
HTSlib CRAM reader has out-of-bounds read due to improper validation of input
HTSlib is a library for reading and writing bioinformatics file formats. CRAM is a compressed format which stores DNA sequence alignment data. In the cram_decode_slice() function called while reading CRAM records, the value of the mate reference id field was not validated. Later use of this value, for example when converting the data to SAM format, could result in the out of bounds array reads when looking up the corresponding reference name. If the array value obtained also happened to be a valid pointer, it would be interpreted as a string and an attempt would be made to write the data as part of the SAM record. This bug may allow information about program state to be leaked. It may also cause a program crash through an attempt to access invalid memory. Versions 1.23.1, 1.22.2 and 1.21.1 include fixes for this issue. There is no workaround for this issue.
Attack profile
How easy it is to exploit
- Attack vector
- Network
- Complexity
- Low
- Privileges needed
- None
- User interaction
- None
What an attacker can affect
- Confidentiality
- Low
- Integrity
- None
- Availability
- Low
Exploit likelihood
What each source reports
CVE List Score used
6.9
HTSlib CRAM reader has out-of-bounds read due to improper validation of input
HTSlib is a library for reading and writing bioinformatics file formats. CRAM is a compressed format which stores DNA sequence alignment data. In the cram_decode_slice() function called while reading CRAM records, the value of the mate reference id field was not validated. Later use of this value, for example when converting the data to SAM format, could result in the out of bounds array reads when looking up the corresponding reference name. If the array value obtained also happened to be a valid pointer, it would be interpreted as a string and an attempt would be made to write the data as part of the SAM record. This bug may allow information about program state to be leaked. It may also cause a program crash through an attempt to access invalid memory. Versions 1.23.1, 1.22.2 and 1.21.1 include fixes for this issue. There is no workaround for this issue.
- Record
CVE-2026-31967- CVSS 4.0
- 6.9 Medium
CVSS:4.0/AV:N/AC:L/AT:N/PR:N/UI:N/VC:L/VI:N/VA:L/SC:N/SI:N/SA:N - Weakness
- CWE-125, CWE-129
- Updated
- 2026-11-02
EUVDEUVD-2026-12938
6.9
HTSlib is a library for reading and writing bioinformatics file formats. CRAM is a compressed format which stores DNA sequence alignment data. In the cram_decode_slice() function called while reading CRAM records, the value of the mate reference id field was not validated. Later use of this value, for example when converting the data to SAM format, could result in the out of bounds array reads when looking up the corresponding reference name. If the array value obtained also happened to be a valid pointer, it would be interpreted as a string and an attempt would be made to write the data as part of the SAM record. This bug may allow information about program state to be leaked. It may also cause a program crash through an attempt to access invalid memory. Versions 1.23.1, 1.22.2 and 1.21.1 include fixes for this issue. There is no workaround for this issue.
- Record
EUVD-2026-12938- CVSS 4.0
- 6.9 Medium
CVSS:4.0/AV:N/AC:L/AT:N/PR:N/UI:N/VC:L/VI:N/VA:L/SC:N/SI:N/SA:N - Updated
- 2026-11-02
NVD
6.9
HTSlib is a library for reading and writing bioinformatics file formats. CRAM is a compressed format which stores DNA sequence alignment data. In the cram_decode_slice() function called while reading CRAM records, the value of the mate reference id field was not validated. Later use of this value, for example when converting the data to SAM format, could result in the out of bounds array reads when looking up the corresponding reference name. If the array value obtained also happened to be a valid pointer, it would be interpreted as a string and an attempt would be made to write the data as part of the SAM record. This bug may allow information about program state to be leaked. It may also cause a program crash through an attempt to access invalid memory. Versions 1.23.1, 1.22.2 and 1.21.1 include fixes for this issue. There is no workaround for this issue.
- Record
CVE-2026-31967- CVSS 4.0
- 6.9 Medium
CVSS:4.0/AV:N/AC:L/AT:N/PR:N/UI:N/VC:L/VI:N/VA:L/SC:N/SI:N/SA:N/E:X/CR:X/IR:X/AR:X/MAV:X/MAC:X/MAT:X/MPR:X/MUI:X/MVC:X/MVI:X/MVA:X/MSC:X/MSI:X/MSA:X/S:X/AU:X/R:X/V:X/RE:X/U:X - CVSS 3.1
- 9.1 Critical
CVSS:3.1/AV:N/AC:L/PR:N/UI:N/S:U/C:H/I:N/A:H - Weakness
- CWE-125, CWE-129
- Updated
- 2026-11-02
OSV
6.9
HTSlib CRAM reader has out-of-bounds read due to improper validation of input
HTSlib is a library for reading and writing bioinformatics file formats. CRAM is a compressed format which stores DNA sequence alignment data. In the cram_decode_slice() function called while reading CRAM records, the value of the mate reference id field was not validated. Later use of this value, for example when converting the data to SAM format, could result in the out of bounds array reads when looking up the corresponding reference name. If the array value obtained also happened to be a valid pointer, it would be interpreted as a string and an attempt would be made to write the data as part of the SAM record. This bug may allow information about program state to be leaked. It may also cause a program crash through an attempt to access invalid memory. Versions 1.23.1, 1.22.2 and 1.21.1 include fixes for this issue. There is no workaround for this issue.
- Record
CVE-2026-31967- CVSS 4.0
- 6.9 Medium
CVSS:4.0/AV:N/AC:L/AT:N/PR:N/UI:N/VC:L/VI:N/VA:L/SC:N/SI:N/SA:N - Weakness
- CWE-125, CWE-129
- Updated
- 2026-11-02
OSVDEBIAN-CVE-2026-31967
9.1
HTSlib is a library for reading and writing bioinformatics file formats. CRAM is a compressed format which stores DNA sequence alignment data. In the cram_decode_slice() function called while reading CRAM records, the value of the mate reference id field was not validated. Later use of this value, for example when converting the data to SAM format, could result in the out of bounds array reads when looking up the corresponding reference name. If the array value obtained also happened to be a valid pointer, it would be interpreted as a string and an attempt would be made to write the data as part of the SAM record. This bug may allow information about program state to be leaked. It may also cause a program crash through an attempt to access invalid memory. Versions 1.23.1, 1.22.2 and 1.21.1 include fixes for this issue. There is no workaround for this issue.
- Record
DEBIAN-CVE-2026-31967- CVSS 3.1
- 9.1 Critical
CVSS:3.1/AV:N/AC:L/PR:N/UI:N/S:U/C:H/I:N/A:H - Updated
- 2026-11-02
OSVUBUNTU-CVE-2026-31967
6.9
HTSlib is a library for reading and writing bioinformatics file formats. CRAM is a compressed format which stores DNA sequence alignment data. In the cram_decode_slice() function called while reading CRAM records, the value of the mate reference id field was not validated. Later use of this value, for example when converting the data to SAM format, could result in the out of bounds array reads when looking up the corresponding reference name. If the array value obtained also happened to be a valid pointer, it would be interpreted as a string and an attempt would be made to write the data as part of the SAM record. This bug may allow information about program state to be leaked. It may also cause a program crash through an attempt to access invalid memory. Versions 1.23.1, 1.22.2 and 1.21.1 include fixes for this issue. There is no workaround for this issue.
- Record
UBUNTU-CVE-2026-31967- CVSS 4.0
- 6.9 Medium
CVSS:4.0/AV:N/AC:L/AT:N/PR:N/UI:N/VC:L/VI:N/VA:L/SC:N/SI:N/SA:N - CVSS 3.1
- 9.1 Critical
CVSS:3.1/AV:N/AC:L/PR:N/UI:N/S:U/C:H/I:N/A:H - Updated
- 2026-11-02
Affected products
Affected packages
| Package | Affected | Fixed |
|---|---|---|
htslibDebian:12 |
All versions, plus listed versions 1.16+ds-31.17+ds-0+exp11.17+ds-11.18+ds-0+exp11.18+ds-1 Show 15 moreShow less1.19+ds-0+exp01.19+ds-11.19+ds-1+exp11.19+ds-1.11.20+ds-11.20+ds-21.21+ds-0+exp11.21+ds-0+exp21.21+ds-11.22.1+ds-11.22.1+ds-21.22.1+ds2-11.24-11.24-21.24-3 |
None known |
htslibDebian:13 |
All versions, plus listed versions 1.21+ds-11.22.1+ds-11.22.1+ds-21.22.1+ds2-11.24-11.24-21.24-3 |
None known |
htslibDebian:14 |
before 1.24-2, plus listed versions 1.21+ds-11.22.1+ds-11.22.1+ds-21.22.1+ds2-11.24-1 |
1.24-2 |
htslibUbuntu:Pro:14.04:LTS |
All versions, plus listed versions 0.2.0~rc3-10.2.0~rc3-1ubuntu0.1~esm1 |
None known |
htslibUbuntu:Pro:16.04:LTS |
All versions, plus listed versions 1.2.1-11.2.1-21.2.1-2ubuntu11.2.1-2ubuntu1+esm1 |
None known |
htslibUbuntu:Pro:18.04:LTS |
All versions, plus listed versions 1.5-11.5-4ubuntu11.6-3ubuntu11.6-41.6-4build11.7-21.7-2ubuntu0.1~esm1 |
None known |
htslibUbuntu:20.04:LTS |
All versions, plus listed versions 1.9-101.9-111.9-121.10.2-2ubuntu11.10.2-2ubuntu21.10.2-31.10.2-3ubuntu0.1 |
None known |
htslibUbuntu:22.04:LTS |
All versions, plus listed versions 1.13+ds-21.13+ds-2build1 |
None known |
htslibUbuntu:24.04:LTS |
All versions, plus listed versions 1.17+ds-11.18+ds-11.19+ds-1.1build21.19+ds-1.1build3 |
None known |
htslibUbuntu:25.10 |
All versions, plus listed versions 1.21+ds-1 |
None known |
htslibUbuntu:26.10 |
All versions, plus listed versions 1.22.1+ds2-11.22.1+ds2-1build1 |
None known |
htslibUbuntu:26.04:LTS |
All versions, plus listed versions 1.21+ds-11.22.1+ds2-1 |
None known |
History
| Recorded | Changed | Sources |
|---|---|---|
| first indexed | CVE List, EUVD, NVD, OSV |
Dates are when Every CVE recorded each change. Upstream dates may differ.
In short
CVE-2026-31967 is a medium vulnerability (CVSS 6.9) in Htslib, published March 18, 2026. No source lists public exploit code. EPSS puts the chance of exploitation in the next 30 days at 0.47%, the 41st percentile. Fixed in htslib 1.24-2.
References
github.com/samtools/htslib/security/advisories/GHSA-33x5-c6vj-8f2w
github.com/samtools/htslib/commit/9cefb46453ad471e933b8212d4f45920524d3357
github.com/CVEProject/cvelistV5/tree/main/cves/2026/31xxx/CVE-2026-31967.json
nvd.nist.gov/vuln/detail/CVE-2026-31967
security-tracker.debian.org/tracker/CVE-2026-31967
ubuntu.com/security/CVE-2026-31967
cve.org/CVERecord?id=CVE-2026-31967